Treatments of Colon Cancer
From the National Cancer Institute

How cancer of the colon is treated

There are treatments for all patients with cancer of the colon. Three kinds of treatments are available:

Surgery is the most common treatment of all stages of cancer of the colon. A doctor may take out the cancer from the colon using one of the following:

 

If the cancer is found at a very early stage, the doctor may take out the
cancer without cutting into the abdomen. Instead, the doctor may put a
tube through the rectum into the colon and cut the tumor out. This is
called a local excision. If the cancer is found in a small bulging piece of
tissue (called a polyp), the operation is called a polypectomy.
If the cancer is larger, the doctor will take out the cancer and a small
amount of healthy tissue around it (bowel or colon resection). The healthy
parts of the colon are then sewn together (anastomosis). The doctor will
also take out lymph nodes near the intestine and look at them under the
microscope to see if they contain cancer.
If the doctor is not able to sew the colon back together, he or she will
make an opening (stoma) on the outside of the body for waste to pass out of
the body. This is called a colostomy. Sometimes, the colostomy is only
needed until the colon has healed, and then it can be reversed. However,
the doctor may have to take out the entire lower colon and the colostomy is
permanent. If a patient has a colostomy, a special bag will need to be worn
to collect body wastes. This special bag, which sticks to the skin around
the stoma with a special glue, can be thrown away after it is used. This bag
does not show under clothing, and most people take care of these bags
themselves.

Radiation therapy is the use of x-rays or other high-energy rays to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external radiation therapy) or from putting materials that contain radiation through thin plastic tubes (internal radiation therapy) in the intestine area. Radiation can be used alone or in addition to surgery and/or chemotherapy.

Chemotherapy is the use of drugs to kill cancer cells. Chemotherapy may be taken by pill, or it may be put into the body by inserting a needle into a vein. A patient may be given chemotherapy through a tube that will be left in the vein while a small pump gives the patient constant treatment over a period of weeks. Chemotherapy is called a systemic treatment because the drug enters the bloodstream, travels through the body, and can kill cancer cells outside the colon. If the cancer has spread to the liver, the patient may be given chemotherapy directly into the artery going to the liver.

If the doctor removes all the cancer that can be seen at the time of the operation, the patient may be given chemotherapy after surgery to kill any cancer cells that are left. Chemotherapy given after an operation to a person who has no cancer cells that can be seen is called adjuvant chemotherapy.

Biological treatment tries to get the body to fight cancer. It uses materials made by the body or made in a laboratory to boost, direct, or restore the body's natural defenses against disease. Biological treatment is sometimes called biological response modifier (BRM) therapy or immunotherapy.


Treatment by stage

Treatments for cancer of the colon depend on the stage of the disease and the patient's general health.

Standard treatment may be considered because of its effectiveness in patients in past studies, or participation in a clinical trial may be considered. Not all patients are cured with standard therapy and some standard treatments may have more side effects than are desired. For these reasons, clinical trials are designed to find better ways to treat cancer patients and are based on the most up-to-date information. Clinical trials are ongoing in most parts of the country for most stages of cancer of the colon. To learn more about clinical trials, call the Fitzpatrick Cancer Center at 562-7120.


STAGE 0 COLON CANCER

Treatment may be one of the following:

1. Local excision or simple polypectomy to remove all the cancer.

2. Bowel resection.

STAGE I COLON CANCER

Treatment is usually surgery (bowel resection) to remove the cancer and join the cut ends of the bowel.


STAGE II COLON CANCER

Treatment may be one of the following:

1. Treatment is usually surgery (bowel resection) to remove the cancer.

2. Clinical trials of chemotherapy, radiation therapy, or biological therapy following surgery.

3. If the tumor has spread to nearby tissue, a patient may also receive chemotherapy and/or radiotherapy following surgery.

STAGE III COLON CANCER

Treatment may be one of the following:

1. Treatment is usually surgery (bowel resection) to remove the cancer followed by chemotherapy.

2. Clinical trials of chemotherapy, radiation therapy, and/or biological therapy following surgery.

STAGE IV COLON CANCER

Treatment may be one of the following:

1. Surgery (bowel resection) to remove the cancer or to make the colon go around the cancer so that it can still work.

2. Surgery to remove parts of other organs such as the liver, lungs, and ovaries, where the cancer may have spread.

3. Radiation therapy to relieve symptoms.

4. Chemotherapy to relieve symptoms.

5. Clinical trials of chemotherapy or biological therapy.

RECURRENT COLON CANCER

If the cancer has come back (recurred) in only one part of the body, treatment may consist of an operation to take out the cancer. If the cancer has spread to several parts of the body, a doctor may give a patient either chemotherapy or radiation therapy. The patient may also choose to participate in a clinical trial testing new chemotherapy drugs or biological therapy.


TO LEARN MORE

TO LEARN MORE..... CALL 518 562-7120

The following booklet about cancer of the colon may be helpful:

    What You Need To Know About Cancer of the Colon and Rectum

The following general booklets on topics related to cancer may also be helpful:

What You Need To Know About Cancer
Taking Time: Support for People with Cancer and the People Who Care About Them
What Are Clinical Trials All About?
Chemotherapy and You: A Guide to Self-Help During Treatment
Radiation Therapy and You: A Guide to Self-Help During Treatment
Eating Hints for Cancer Patients
Advanced Cancer: Living Each Day
When Cancer Recurs: Meeting the Challenge Again

There are many other places where people can get materials and information about cancer treatment and services. The social service office at a hospital can be checked for local and national agencies that help with getting information about finances, getting to and from treatment, getting care at home, and dealing with problems.

For more information from the National Cancer Institute, please write to this address:  

National Cancer Institute
Office of Cancer Communications
31 Center Drive, MSC 2580
Bethesda, MD 20892-2580

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